Centrifuge Application Solution for the Pharmaceutical Industry

Traditional Chinese Medicine (TCM) Extraction & Residue Treatment

Application:

Dehydration of medicinal residues post-extraction (e.g., herbal pastes, spent herbs).

Industry Challenges:

• Low efficiency in traditional filtration, leading to 15-20% active ingredient loss.

• High moisture content (>65%) in residues increases drying costs.

• Clogging risks in viscous or fibrous herbal extracts.

Customized Solutions:

• High-Speed Decanter Centrifuges

Variable pitch screw design for 40% higher throughput.

CIP (Clean-in-Place) system compliant with GMP standards.

Reduces moisture content to ≤55%, cutting drying energy costs by 30%.

• Key Innovations:

Corrosion-resistant ceramic bowl (3x longer lifespan in acidic extracts).

AI-powered speed control (adjusts differential speed from 0.5-15 RPM for optimal separation).

Biopharmaceutical Processing

Applications:

Cell culture harvest (mAb, vaccines).

Fermentation broth clarification.

Biomass recovery in microbial production.

Critical Requirements:

Gentle processing to maintain cell viability (>95%).

Sterility assurance (ISO Class 5 clean room compatibility).

Handling varying solid loads (5-25% w/v).

Precision Separation Systems:

Disc Stack Centrifuges

Hermetic α-2 seals preventing aerosol contamination.

Low-shear technology: <5% product degradation.

Integrated optical sensors for real-time turbidity monitoring.

Advanced Features:

Chilled separation (4-10°C) for thermolabile compounds.

Three-phase separation (simultaneous recovery of supernatant, pellets, and inter phase).

FDA 21 CFR Part 11 compliant data logging.